The Significance of Ventilation in BSL-2 and BSL-3 Laboratories: Ensuring Containment, Safety, and Operational Integrity in Pathogen Handling Facilities

Executive Summary Ventilation systems are the primary engineering control in high containment laboratories. They manage airborne hazards, prevent environmental contamination, and protect personnel. This white paper explains how ventilation supports design, and operation, with emphasis on airflow control, pressure cascading, filtration, and regulatory compliance. 1. Introduction Ventilation is both a functional necessity and a statutory [...]